Mid-infrared (Mid-IR) lasers have experienced substantial progress in the past decade for various emerging applications. Mid-IR wavelength coincides with the molecular resonant peaks, namely molecular fingerprints, which makes Mid-IR lasers useful for spectroscopic and biomedical applications. In addition, with a large ponderomotive force, few-cycle Mid-IR pulses serve as the idea tool for strong-field physics and ultrafast electronics science. This special session aims to bring together researchers from diverse backgrounds to create synergy in this important research area. Topics Novel Mid-IR Sources and Techniques Nonlinear Frequency Conversion and Parametric Sources Nonlinear and Laser Materials for Mid-IR Ultrashort Mid-IR Pulses and Frequency Combs Mid-IR Supercontinuum Generation Mid-IR fibers and fiber lasers Mid-IR Integrated Photonics New Sources and Techniques for Mid-IR Spectroscopy Mid-IR sensing, Imaging and Spectroscopy Strong-field Physics Pumped by Mid-IR Laser Biomedical Applications of Mid-IR Lasers Novel Techniques of Mid-IR spectral and temporal measurement ...